The COVID-19 Oxford Vaccine Trial is run by the University of Oxford's Jenner Institute and the Oxford Vaccine Group clinical teams. The trial and research center is conducted in collaboration with multiple study sites across the UK and internationally, including a temporary research installation on the University grounds.

The organization knew it needed tight security surrounding the facility to mitigate risk and ensure the safety of staff and assets. Leaders within the University recommended First Response Group (FRG) after they had used the company's security resources on campus during the first national lockdown amid the COVID-19 pandemic.

After a full site risk assessment, FRG recommended a 24/7 manned security detail consisting of three security officers during the day and two at night, to ensure protection for the trial patients, research staff and sensitive clinical data. At the vaccine trial and research facility FRG’s SIA (Security Industry Authority) licensed security officers are tasked with controlling all entrances and exits through the facility day and night, as well as ensuring distancing measures are followed and monitoring the area for any suspicious activity.

To ensure fast and consistent communication with the University, FRG implemented a dedicated site supervisor providing a senior level FRG presence onsite Monday to Friday to act as the main onsite point of contact for the University, dealing with any issues as they arise in real time.